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Title: Maternal protein restriction and maternal age in the nutritional programming of obesity in rats
Author: Ware, Samantha
ISNI:       0000 0004 5359 9475
Awarding Body: University of Nottingham
Current Institution: University of Nottingham
Date of Award: 2014
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Obesity is a major global and national problem with a variety of consequences and effects. The relationship of fetal programming with obesity has been discovered through both human and animal studies and it has been found that nutritional programming can predispose the developing offspring to obesity later in life. However, many aspects of this fetal programming have yet to be fully determined, for instance the environmental and metabolic factors involved. This thesis has investigated the programming effects of maternal low protein restriction (MLP) and maternal age (2 month, 4 month and 6-9 month old mothers) in the rat, looking at both immature (4 weeks old) and mature (9 months old) adult offspring. Postnatal high fat diets were fed for 9 weeks to exacerbate potential obesogenic effects. During the trials various measures were studied, body weight, feed intake, energy expenditure, metabolism, body composition, body fat distribution, activity and behaviour.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available