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Title: Role of physico-chemical environmental factors in the emergence and development of insecticides resistant mosquito in Nigeria
Author: Imam, Abdullahi A.
Awarding Body: University of Abertay Dundee
Current Institution: Abertay University
Date of Award: 2013
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The aim of this study is to investigate the role of physico-chemical environmental factors present in mosquito breeding ecologies as sources of selection pressure for the emergence and development of insecticides resistance in Anopheles gambiae from Northern Nigeria. Prospecting for, and sampling of An. gambiae larvae was carried out from many breeding sites in towns and villages spread out across Kano and Jigawa states of Northern Nigeria. The breeding sites visited and sampled were grouped into three study zones according to the type of human related activities taking place around the mosquito breeding environments. Larval densities (per litre of breeding water) and water chemistry analysis were carried out from all the breeding sites visited. Detoxification enzymes; Cytochrome P4S0, Glutathione S-transferases and Esterases as well as glutathione assays were carried out on the three life stages of the sampled An. gambiae using the relevant assay protocols. The results showed that the levels of the physical environmental factors; pH, temperature, conductivity, transparency, dissolved oxygen and biological oxygen demand did not vary significantly (p<0.05) across the three studied zones. The levels of the chemical environmental factors; total dissolved solids, sulphate, phosphate, nitrite and nitrate ions were significantly (p0.05) higher in study zone A compare to the other two zones, while carbon content and oil and grease were significantly (p<0.05) distributed in study C than the other two zones. Likewise, the activity of P4S0s was higher in study zone C while those of GST and CEs were significantly (p
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available