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Title: Fibro-osseous lesions affecting the jaws
Author: MacDonald, David Stanislaw
Awarding Body: University of Edinburgh
Current Institution: University of Edinburgh
Date of Award: 2007
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Fibro-osseous lesions (FOLs) affecting the jaws represent an important category both diagnostically and therapeutically. The overwhelming majority of cases of cemento-osseus dysplasia (COD) require no treatment, whereas its florid (affects more than one sextants of the jaw) form, in particular, raises significant risk of prosthodontic failure in the elder patient. The cemento-ossifying fibroma (COF) is a benign, occasionally aggressive, neoplasm requiring complete enucleation to obviate recurrence.  Fibrous dysplasia (FD) is a harmatoma in most cases, but on occasion displays neoplastic behaviour. Diagnosis is normally achieved upon both clinical and radiological evaluation. Aims: Review the consecutive case of these lesions affecting a Hong Kong population, almost exclusively Chinese, whose oral lesions until only recently have not featured prominently in the international literature. Conduct a systematic review (SR) on the world literature pertaining to FOLs. Materials and Methods: all consecutive cases on CODs, COFs and FDs managed at the Dental School of the University of Hong Kong (HKU) from 1982 to 1992 for CODs and onwards to 2004 for COFs and FDs were identified. Results: Twenty-three Florid CODs, 6 Focal CODs, 24 COFs and 21 FDs (1 bimaxillary) were identified and their clinical and radiological features analysed and inserted into the SRs. All Florid CODs and COFs were female. Florid CODs identified as incidental findings and retained in radiology files were significantly younger than those derived from pathology files. COFs in the SR had significant predilections for females and the mandible and to be detected as radiolucencies, whereas the FD more significantly displayed radiologically, expansion of the buccolingual cortices, and of the lower border of the mandible. Clinically, the Florid CODs were significantly associated with pain, FDs were more significantly associated with swelling, FocCODs were also more significantly found incidentally.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (D.D.S.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available