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Title: The chromosomal beta-lactamases of the genus Acinetobacter
Author: Hood, John
Awarding Body: University of Edinburgh
Current Institution: University of Edinburgh
Date of Award: 1992
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The evolution of the Host-Parasite relationship in terms of the fascinating interaction of the evolution of the host and parasite over the last 50 years is considered. This includes the evolution of new therapies such as intensive care and new drugs. The shifts in the sort of pathogens causing nosocomial infection and the evolution of their resistance mechanisms to antimicrobial agents are described. The various classification schemes for β-lactamases are reviewed. The evolution and origin of β-lactamases are discussed. The newer forms of resistance mediated to third generation cephalosporins are evaluated. Finally the introduction considers briefly the genus Acinetobacter with particular reference to its 'up and coming' status as a problematical nosocomial pathogen and the taxonomic chaos that surrounds it.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available