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Title: The identification and estimation of prostaglandins and their metabolites
Author: Hensby, C. N.
Awarding Body: University of Edinburgh
Current Institution: University of Edinburgh
Date of Award: 1977
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Three attempts at developing a radioimmunoassay for prostaglandin E were made. Two of these attempts resulted in the production of anti-sera directed mainly to prostaglandin B. The third attempt was designed to produce anti-sera specfic to prostaglandin F, a prostaglandin readily formed from prostaglandin E by reduction with sodium borohydride. The influence of age, sex and hormonal state have been studied with reference to the reduction of prostaglandin E to prostaglandin F by the enzyme systems present in sheep blood and liver samples from chicken, rabbit and guinea-pig. Ovarian steroid hormones have been found to influence the enzyme activity and preliminary evidence would suggest a link between these hormones and prostaglandin metabolism.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available