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Title: An adaptation of interpersonal psychotherapy for depression within primary care (IPT-Brief) : a randomised trial of IPT-B versus waiting list control in the treatment of major depressive disorder
Author: Graham, Patricia A. M.
Awarding Body: University of Edinburgh
Current Institution: University of Edinburgh
Date of Award: 2002
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The original 16-session model of Interpersonal Psychotherapy for Depression (IPT: Klerman, Weissman, Roundsaville and Chevron, 1984) was adapted to an abbreviated 8-session version (IPT-B) and initially applied to a single-case pilot study, prior to the present randomised trial. The adaptation was carried out in response to the findings of Shapiro et al. (1994) in which mildly to moderately depressed patients showed strong, positive outcomes, regardless of whether they had received 8 or 16 sessions of either cognitive-behavioural or psychodynamic-interpersonal psychotherapy. A total of 49 depressed patients were randomly allocated to one of two groups: (1) IPT-B or (2) waiting list control. Patients in the IPT-B group demonstrated a reduction of severity of depression at a higher rate than would be expected to occur with the passage of time alone. There was no evidence however, of a differential improvement in the perceived quality of interpersonal relationships. Secondary analyses demonstrated that, when stratified for severity, severely depressed patients in the IPT-B group exhibited greater improvement than those who were less severely depressed in the same group. By two-month follow-up, 73% of all IPT-B patients made what was considered to be a clinically significant improvement. The effectiveness of IPT-B was witnessed by the NNT result of less than one, for both self-report and clinician-rated clinically significant change. The economic evaluation extended these findings and demonstrated the relative cost effectiveness of IPT-B as compared to an estimated standard clinical practice of CBT. Implications of the results are discussed and further research with IPT-B is suggested to determine whether (a) an extended follow up period will demonstrate improvement in the quality of relationships; (b) it will outperform alternative active treatments, such as 16 sessions of standard IPT, CBT and/or pharmacotherapy (c) other patient characteristics will predict reliable change and/or severity of outcome.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (D.Clin.Psy.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available