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Title: The role of the exoribonuclease Pacman/Xrn1 in wing development in Drosophila
Author: Waldron, Joseph Alexander
ISNI:       0000 0004 5361 4989
Awarding Body: University of Brighton
Current Institution: University of Brighton
Date of Award: 2014
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RNA stability plays a critical role in the control of gene regulation by determining the levels of mRNA that can be translated into protein. The aim of this thesis is to investigate the role of the exoribonuclease Pacman in regulating gene expression during wing development in Drosophila melanogaster. Pacman is the only known cytoplasmic exoribonuclease which degrades RNA in a 5’‐3’ direction and is highly conserved across all eukaryotes.
Supervisor: Not available Sponsor: Medical Research Council
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: A000 Medicine