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Title: An investigation of granulated sugar dressing in the management of sloughy, necrotic and infected exuding wounds
Author: Murandu, Moses Donald
ISNI:       0000 0004 5361 0048
Awarding Body: University of Birmingham
Current Institution: University of Birmingham
Date of Award: 2015
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Aim: Investigated the use of granulated sugar in the management of sloughy, necrotic and infected exuding wounds. Method: The investigation followed the Medical Research Council (MRC, 2007) framework for investigation of complex interventions. Pre-clinical: The study was registered with MHRA, followed by development and design of the mode of sugar delivery to patient use. Evidence review: A systematic review and meta-analysis concluded that there was no existing good quality evidence to support the routine use of sugar dressings. Phase I: Laboratory studies found that all three sugars showed relatively equal activity against all the bacteria tested although Demerara sugar was slightly less active. Phase II: A feasibility study of 22 patients concluded that both insulin and non-insulin treated diabetic patients can be treated with sugar dressing without affecting their blood sugar levels. Phase III: A randomised controlled trial failed to recruit the intended numbers and final analysis was carried out on 22 patients randomised to sugar and 19 randomised to usual care. 19 (86%) achieved debridement at 4 weeks in the sugar group compared to 6 (32%) standard care group (Fisher’s exact test: p<0.001). Overall conclusion: Sugar has an effect on micro-organisms and can be used in modern hospitals and community settings.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: R Medicine (General) ; RT Nursing