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Title: Simulating the lytic-lysogenic switch in bacteriophage λ
Author: Andrews, Robert Michael
Awarding Body: University of Edinburgh
Current Institution: University of Edinburgh
Date of Award: 1999
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A computer-based simulation of the lytic-lysogenic switch in bacteriophage λ, has been built. The simulation uses information form the λ DNA sequence, as well as kinetic and thermodynamic data from phage experiments, to model λ growth. This thesis has involved three stages of investigation. (1) Building the model from what we know - our knowledge of λ and its behaviour. (2) Testing the model against what we know - comparing in vivo and in silico studies of λ growth. (3) Using the model to perform λ experiments.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available