Use this URL to cite or link to this record in EThOS:
Title: Synthesis, DNA interactions and cytotoxicity of novel chloroethylaminoanthraquinones
Author: Paniwnyk, Zennia
Awarding Body: De Montfort University
Current Institution: De Montfort University
Date of Award: 2000
Availability of Full Text:
Access from EThOS:
Access from Institution:
The design of DNA directed nitrogen mustards has led to the development of compounds with increased specificity for DNA and enhanced cytotoxicity compared to similar untargeted mustards. By linking an intercalating anthraquinone chromophore to a nitrogen mustard function it was anticipated that such compounds would also have the potential to irreversibly inhibit the topoisomerase II (topo II) enzyme.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available