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Title: Functionalisation of polystyrene using organolithium and organoboron reagents
Author: Hou, D.
Awarding Body: University of Wales Swansea
Current Institution: Swansea University
Date of Award: 1997
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The thesis deals with the synthesis and applications of two different types of polystyrene-supported sulfonic acids and bis-(2,4,6, -triisopropylphenyl)boranes (abbreviated to ditripylboranes). Some new methods have been developed by using organolithium reagents. Chapter 1 outlines the research project. Chapter 2 introduces the synthesis and applications of polymer-supported catalysts and reagents. Chapter 3 gives a brief review of the preparation of organolithium reagents and intermediates. Chapter 4 discusses the preparation of benzyllithiums in general and reports a superior procedure for generation of benzyllithium and substituted benzyllithiums from the corresponding chlorides. Chapter 5 reports a general and efficient method for the preparation of organic sulfonic acids by insertion of sulfur trioxide into the metal-carbon bond of organolithium compounds. This method can be used for preparation of both aliphatic and aromatic organic sulfonic acids in good yields. Chapter 6 reports new syntheses of two different types of polystyrenesulfonic acids by use of reaction types developed as reported in Chapter 5. Chapter 7 investigates the synthesis of organylditripylboranes and two different types of polymer-supported ditripylboranes. Chapter 8 charts the formation and applications of alkylditripylhydroborates and polymer-supported ditripylhydroborates, which display high diastereoselectivity in the reduction of ketones.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available