Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637157
Title: Improved techniques for isolation of pure cellular organelles with magnetic ferrofluid
Author: Walker, Mathew William
ISNI:       0000 0004 5360 1790
Awarding Body: Cardiff University
Current Institution: Cardiff University
Date of Award: 2015
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Abstract:
Lysosomes are essential cellular organelles known to be the main site for the breakdown and recycling of endocytosed macromolecules within cells. However, our knowledge of lysosomal function has changed considerably over the last decade with the lysosome now being a recognized Ca2+ signaling organelle with additional roles in plasma membrane repair, clearance of defective organelles and mediating cell death as well as established roles in clearing infection. Our ability to study these unique organelles has however been stymied by a dearth of good techniques for the purification of functional lysosomes not contaminated by other organelles.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.637157  DOI: Not available
Keywords: QR Microbiology
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