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Title: An investigation into BORIS expression in prostate cancer cells and its role in epigenetic regulation of the androgen receptor gene
Author: Gupta, Yukti Hari
ISNI:       0000 0004 5358 1558
Awarding Body: University of Essex
Current Institution: University of Essex
Date of Award: 2014
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BORIS, a paralogue of the transcription factor CTCF, is a member of the cancer-testis antigen family. BORIS is normally present in the testes; however, it is aberrantly expressed in various tumours and cell lines. The main aim of this study was to investigate BORIS expression in prostate cell lines and tumours, and the importance of BORIS in the regulation of genes in prostate cells, in particular, the androgen receptor CAR) gene, associated with the development of more aggressive prostate tumours.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available