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Title: The effect of Hydroview lens opacification on vision
Author: Blundell, Michael
Awarding Body: University of Bristol
Current Institution: University of Bristol
Date of Award: 2012
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Cataract surgery is a common operation which involves removing the natural crystalline lens from the eye, when it has become opaque (cataractous), and replacing it with an artificial intraocular lens (IOL). A rare complication that has been associated with some IOLs is opacification.Hydroview (Bausch and Lomb) IOLs were widely implanted during cataract surgery throughout the UK between 1997 and 2001. These IOLs have been associated with symptomatic opacification of the optic necessitating IOL exchange to restore clarity of vision and redress the symptom of glare. As glare and misty vision have been purported as the most common presenting symptoms[1 -4], this thesis investigated the impact of IOL opacification on vision. To this end I interrogated the effect of IOL opacification on subjective visual symptoms, objective measurements of visual function and vision related quality of life, as well as measuring the beneficial effect or not of IOL exchange surgery on these variables. The study also investigated the possible aetiology of Hydroview opacification. I assessed the association of patient, surgical and lens related factors with the incidence of opacification. Explanted lenses were examined with a scanning electron microscope fitted with a wavelength dispersive x-ray probe to describe the ultrastructural findings and elemental analysis of opacified and clear hydroview IOLs to elucidate major contributing factors or underlying causes of opacification.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (M.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available