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Title: A system wide study on the hypertrophic response to salbutamol in skeletal muscle cells
Author: Kenyani, Jenna
Awarding Body: University of Liverpool
Current Institution: University of Liverpool
Date of Award: 2012
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Salbutamol was synthesised in 1967 and is widely known now as a Beta-adrenergic agonist. It is known that p-agonists cause hypertrophy in various mammalian muscles cells, however the mechanisms by which this occurs are not fully understood. Recent studies have suggested that there is great potential for using Beta-agonists, specifically Beta-agonists, in restoring muscle mass and strength in humans. Although, salbutamol is commonly used as a bronchodilator, it has heen identified as having an effect on muscle growth at a dose which is safe for humans. However, like all steroids there are many side effects associated with Beta-agonists. By understanding the mechanisms affected within muscle cells by treatment with salbutamol it will enable not only the understanding of muscle hypertrophy but lead to more specific drugs being designed.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available