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Title: Modelling the effect of common mental disorders on child growth in Butajira, Ethiopia
Author: Medhin Tesfay, Girmay
Awarding Body: King's College London (University of London)
Current Institution: King's College London (University of London)
Date of Award: 2012
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Background: Evidence about the effects of perinatal common mental disorders (CMD) on child growth is consistent in South Asian studies but not in Sub Saharan Africa. Aims: To (1) assess the effect of CMD on child growth in Ethiopia using traditional analysis, latent growth modelling (LGM) and multilevel growth modelling (MGM) techniques, and (2) evaluate the effects of other pre-specified risk factors on infant growth using these three modelling techniques Methods: A population based cohort was established between July 2005 and February 2006 in a demographic surveillance site in Butajira, Ethiopia, recruiting 1065 women in pregnancy and followed them with their newly born infants. Main exposure was perinatal CMD measured with locally validated self reporting questionnaire (SRQ-20). The women were interviewed at recruitment, birth, two and 12 months postnatal. In addition to birthweight, infant growth was monitored at two, six, nine, 12 and 18 months of age and standardized using 2006 WHO reference standards. Logistic regression and linear regression were used to model binary and continous infant growth outcomes, respectively, at two, six and twelve months of age. Furthermore, infant growth over the first 18 months of age and predictors of growth patters of these infants were investigated using MGM and LGM. Results: Postnatal and persistent CMD were significant risk factors of compromised initial infant length, and part of the effect on the total length gain was mediated through diarrhoeal episodes. Early infant feeding practices and birthweight did not mediate the effects of CMD on infant growth. Boys perform better in initial weight (in kg) and length (in cm), but worse in initial values of standardized growth measures. Low birthweight and reduced maternal mid upper arm circumference during pregnancy were significant predictors of compromised initial growth.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available