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Title: Learning-dependent plasticity in the human visual system
Author: Ditye, T.
ISNI:       0000 0004 5363 6504
Awarding Body: University College London (University of London)
Current Institution: University College London (University of London)
Date of Award: 2014
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The capability to change is an inherent property of the human brain. Plastic processes occur throughout the central nervous system and are a requirement for development, learning, and the formation of memories. The research presented in this thesis examined learning-dependent plasticity in the visual system. Mechanisms of interest included structural and functional brain plasticity, adaptation, and the facilitating functions of sleep in supporting the processing, implementation, and organisation of newly learned information and experiences. Some of the most traditional experimental paradigms such as visual search, sensory adaptation, and texture discrimination were utilised to trigger learning and the accompanying changes in behaviour, neural function, and brain anatomy. Results based on behavioural data and high-resolution brain imaging data showed that training in a variety of visual tasks can result in characteristic short-term adjustments of cortical volume and myelination in task-relevant brain regions which can be correlated with individual improvements in task performance. Our research further demonstrated that sleep is a requirement for the integration of adaptive visual experiences, thereby linking adaptation---a mechanism usually not considered to play a role in mnemonic processes---with learning and memory.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available