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Title: Olive leaf phenolics and cardiovascular risk reduction
Author: Lockyer, Stacey
ISNI:       0000 0004 5361 5674
Awarding Body: University of Reading
Current Institution: University of Reading
Date of Award: 2014
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Olive leaf extract (OLE) contains polyphenols unique to the olive plant (Olea europaea), namely the secoiridoid oleuropein and its derivative hydroxytyrosol (HT). As such, OLE contains a similar phenolic profile to olive oil. Early evidence suggests some beneficial effects of OLE on human health. We conducted a double-blind, controlled, cross over, postprandial study, in which healthy individuals (n=18) consumed OLE capsules containing 58 mg oleuropein and 4 mg HT or a control. Arterial stiffness, measured by Digital Volume Pulse, and the production of inflammatory cytokine interleukin-8 (IL-8), measured in LPS-stimulated whole blood cultures (WBC), were both significantly reduced (p
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available