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Title: The Confidential Enquiry into Perioperative Equine Fatalities : a prospective multicentre cohort study of equine perioperative mortality
Author: Johnston, G. M.
Awarding Body: University of Cambridge
Current Institution: University of Cambridge
Date of Award: 2000
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The Confidential Enquiry into Perioperative Equine Fatalities (CEPEF) was a prospective multicentre cohort study of equine perioperative mortality within seven days of surgery. The study was designed to establish the incidence of equine perioperative morality and identify any predisposing risk factors for non-colic surgery. Records of 41,787 operations under general anaesthesia were submitted by 149 clinics from 19 countries from 1991 to 1996. The total mortality from perioperative complications was 1.9%. The death rate in the 35,927 non-colic operations was 0.95 and was 7.95 for the 5,833 colics. Twenty two different causes of death were identified for non-colics. The most common causes of death were cardiac arrest (32.82%), fracture (23.31%) and myopathy (7.06%). The signalment of the patients undergoing colic surgery were found to be very different from non-colics. Univariate analysis of non-colics for all types of death identified numerous risk factors which were associated with increased or decreased risk of death including age of the patient, drugs used for sedation and induction, clinic type, operation, and day of the week. The most frequent cause of death in equidae, intraoperative cardiac arrest (0.33%), was examined in greater detail in non-colics. Multivariable models were built using logistic regression for two groups of patients; all non colics and a second model for those who received only inhalation maintenance agents. The final model for both groups which included variables for age and gender demonstrated that sedative premedication, induction agent, type of clinic, starting time of anaesthesia, body position and day of the week were all associated with death from cardiac arrest.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available