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Title: New methods for the construction of C-18F bonds
Author: Stenhagen, Ida Sofia Refsholt
ISNI:       0000 0004 5356 5988
Awarding Body: University of Oxford
Current Institution: University of Oxford
Date of Award: 2014
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The main electrophilic source used in radiolabelling is [18F]F2, which is highly reactive, toxic and requires specialist equipment for safe handling. The Gouverneur group has initiated a research programme focused on the preparation of new stable and easy-to-handle N-18F reagents. In the development of [18F]radiolabelling reactions it would be extremely valuable to develop a library of selective N-18F reagents possessing reactivity tailored to the desired chemical transformation. The aim of this thesis is to further assess the scope of electrophilic N- 18F reagents in new transformations for the construction of C-18F bonds.
Supervisor: Gouverneur, Veronique Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: Organic chemistry ; Organometallic Chemistry ; Organic synthesis ; Radiochemistry ; Fluorine-18