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Title: Studies in the synthesis of pyrroloindole alkaloids and the total synthesis of okaramine C
Author: Hewitt, P. R.
Awarding Body: University of Cambridge
Current Institution: University of Cambridge
Date of Award: 2006
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Abstract:
This thesis is divided into six chapters. The first introduces the pyrroloindole alkaloids and reviews previous methods for the synthesis of the pyrroloindole motif. The second chapter describes the development of methodology for the synthesis of the pyrroloindole core and for varying its substitution pattern. The third chapter describes further development of the methodology described in the second chapter and its application in the total synthesis of okaramine C. The fourth chapter describes synthetic efforts towards the total synthesis of CJ-12663, utilising the methodology described in the second chapter.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.603980  DOI: Not available
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