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Title: Investigation of blood flow in the superior mesenteric artery and its potential influence on atheroma and gut ischaemia
Author: Jeays, Adam D.
Awarding Body: University of Sheffield
Current Institution: University of Sheffield
Date of Award: 2006
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Atherosclerosis is the underlying process in coronary heart disease leading to myocardial infarction, and in arterial damage leading to cerebrovascular accidents. It accounts for almost 50% of deaths in the western world. Atherosclerosis is characterised by the presence of fibro-lipid plaques (atheroma) within the vessel wall. Whilst the initiation and progression of atheroma are not fully understood, it is generally accepted that the time-varying haemodynamic wall shear stress (WSS) that the vessel wall is exposed to is important in determining the likelihood of development of an atherosclerotic plaque The superior mesenteric artery (SMA) is the major blood vessel feeding the small intestine; compared to other vessels of similar size, it is largely spared the effects of atherosclerosis.
Supervisor: Hose, Rod ; Lawford, Pat ; Bardhan, K. D. Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available