Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.592242
Title: Health effects of solvent exposure : a study of dockyard painters
Author: Chen, Ruoling
Awarding Body: University of Aberdeen
Current Institution: University of Aberdeen
Date of Award: 1997
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Abstract:
A cohort study was carried out to investigate mortality of 1292 male painters who had worked in a Royal Naval dockyard in Scotland for at least one year during 1950 and 1992. The mortality of the painters were compared to that of general male population of Scotland in 5-year ages and 5-year periods. Among the cohort there were 205 deaths, 58 from cancer. Proportionate mortality ratios suggested elevated risks of death from all cancers (PMR=110, 95%CI 84-143), prostate cancer (225, 83-489), bladder cancer (219, 60-560) and lymphosarcoma and reticulosarcoma (769, 93-2780). Excess deaths also were found from the central nervous system disease (221, 46-645) and ischaemic heart disease (132, 105-164). Standardised mortality ratios from a subcohort of painters born in 1900 and 1929 showed a similar mortality pattern for 123 deaths: SMR for all cancers was 122 (88-165), cancer of lung 112, (64-182), prostate 263, (97-573), bladder 305, (83-782). 953 surviving painters from the dockyard cohort and 953 controls (non-painters randomly selected from the local population) were invited to participate in a questionnaire study of neuropsychological symptoms. In all, 259 painters and 529 controls took part, a practical 56.6% response. The questionnaire included occupational, smoking and alcohol histories, neuropsychological symptoms, and a personality inventory. A significant excess of symptoms was found among painters over controls. The ORs for painters with a high score (12-22) for all neuropsychological symptoms were 2.73 (0.92-8.17) for 1-4 years of exposure, 6.35 (1.66-24.31) for 5-9 years, 7.34 (1.84-29.31) for 10-14 years and 10.22 (2.53-41.20) for 15-41 years, compared with controls after adjustment for age, educational level, smoking, alcohol, neuroticism and social conformity. In multivariate analyses of subjects with high scores against those with lower scores, besides painting exposure and its dose response, smoking was associated with symptoms: OR for psychological symptoms was 1.47, 0.95-2.29 and OR for neurological symptoms was 2.59, 1.39-4.83.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.592242  DOI: Not available
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