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Title: Novel pDNA particles for pulmonary administration
Author: Bains, Baljinder Kaur
Awarding Body: Cardiff University
Current Institution: Cardiff University
Date of Award: 2010
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Methods have been successfully developed and evaluated to aerosolise surfactant-coated pDNA particles and maintain pDNA viability. Furthermore, investigations have demonstrated that the pDNA particles and a transfection agent (DOTAP) can be incorporated into a generic HFA134a formulation and successfully aerosolised using a standard valve and actuator. Further studies demonstrated the performance of these formulations after four week accelerated stability conditions.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available