The main focus of this thesis is to evaluate .k_r(n,\delta)., the minimal number of $r$cliques in graphs with $n$ vertices and minimum degree~$\delta$. A fundamental result in Graph Theory states that a trianglefree graph of order $n$ has at most $n 2/4$ edges. Hence, a trianglefree graph has minimum degree at most $n/2$, so if $k_3(n,\delta) =0$ then $\delta \le n/2$. For $n/2 \leq \delta \leq 4n/5$, I have evaluated $k_r(n,\delta)$ and determined the structures of the extremal graphs. For $\delta \ge 4n/5$, I give a conjecture on $k_r(n,\delta)$, as well as the structures of these extremal graphs. Moreover, I have proved various partial results that support this conjecture. Let $k_r �(n, \delta)$ be the analogous version of $k_r(n,\delta)$ for regular graphs. Notice that there exist $n$ and $\delta$ such that $k_r(n, \delta) =0$ but $k_r �(n, \delta) >0$. For example, a theorem of Andr{\'a}sfai, Erd{\H{o}}s and S{\'o}s states that any trianglefree graph of order $n$ with minimum degree greater than $2n/5$ must be bipartite. Hence $k_3(n, \lfloor n/2 \rfloor) =0$ but $k_3 �(n, \lfloor n/2 \rfloor) >0$ for $n$ odd. I have evaluated the exact value $k_3 �(n, \delta)$ for $\delta$ between $2n/5+12 \sqrt{n}/5$ and $n/2$ and determined the structure of these extremal graphs. At the end of the thesis, I investigate a question in Ramsey Theory. The Ramsey number $R_k(G)$ of a graph $G$ is the minimum number $N$, such that any edge colouring of $K_N$ with $k$ colours contains a monochromatic copy of $G$. The constrained Ramsey number $f(G,T)$ of two graphs $G$ and $T$ is the minimum number $N$ such that any edge colouring of $K_N$ with any number of colours contains a monochromatic copy of $G$ or a rainbow copy of $T$. It turns out that these two quantities are closely related when $T$ is a matching. Namely, for almost all graphs $G$, $f(G,tK_2) =R_{t1}(G)$ for $t \geq 2$.
