Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.521225
Title: Attenuation of quorum sensing using computationally designed polymers
Author: Stavroulakis, Georgios
Awarding Body: Cranfield University
Current Institution: Cranfield University
Date of Award: 2010
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Abstract:
It is generally accepted that the majority of Gram-negative and Gram-positive bacteria communicate via production and sensing of small signal molecules, autoinducers. The ability of bacteria to sense their population density is termed quorum sensing (QS). Quorum sensing controls certain phenotypic traits, particularly virulence factors and biofilm formation. In this project a new solution for the attenuation of quorum sensing which involves selective sequestering of the signal molecules using rationally designed synthetic polymers was explored.
Supervisor: Piletsky, Sergey ; Tothill, I. E. ; Piletsky, E. ; Robinson, G. Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.521225  DOI: Not available
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