Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506243
Title: Electrophysiological and molecular studies of SCN5A mutations related to sick sinus syndrome
Author: Gui, Junhong
Awarding Body: The University of Manchester
Current Institution: University of Manchester
Date of Award: 2009
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Abstract:
SCN5A is the gene encoding the a subunit of the cardiac voltage-gated sodium channel, hNav1.5. The ionic current through this channel, which is responsible for the upstroke of the cardiac action potential, plays an important role in normal cardiac rhythm in the heart. Genetic defects of SCN5A have been linked with several cardiac arrhythmic disorders including sick sinus syndrome (SSS).
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.506243  DOI: Not available
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