Use this URL to cite or link to this record in EThOS:
Title: Novel palladium catalysed [3+2] cycloadditions towards functionalised aza-bicycles
Author: Stott, Andrew James
Awarding Body: Loughborough University
Current Institution: Loughborough University
Date of Award: 2008
Availability of Full Text:
Access from EThOS:
Novel pyrrolidine, indolizidine and azepine ring systems have been prepared via the palladium catalysed [3+2] cycloaddition of cyclic imines with vinylcyclopropanes. The reaction of simple cyclic imines with various functionalised vinylcyclopropanes, provided a range of bicyclic systems, as potential scaffolds for further elaboration. The application of functionalised cyclic imines derived from enecarbamates was limited due to difficulties generating the imine bond. The developed methodology was also employed in the formation of pyrrolooxazinone products, as templates for functionalised proline syntheses.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available