Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505658
Title: An in vitro investigation of how bone marrow stromal cells promote spinal cord repair
Author: Wright, Karina Therese
Awarding Body: Keele University
Current Institution: Keele University
Date of Award: 2009
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Abstract:
Transplantation of bone marrow stromal cells (MSCs) into spinal cord lesions enhances axonal regeneration and promotes functional recovery in animal studies. This thesis has demonstrated that MSCs can be successfully isolated from bone marrow biopsies of donors with spinal cord injury (SCI) and subsequently expanded in monolayer culture. In addition, the mechanisms by which these MSCs, along with those isolated from non-SCI donors, might promote spinal cord repair following transplantation were investigated using in vitro analyses.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.505658  DOI: Not available
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