Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505445
Title: Evolution, genetics and function of Huntingtin gene in Ciona intestinalis
Author: Mohammed Idris, M.
Awarding Body: The Open University
Current Institution: Open University
Date of Award: 2008
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Abstract:
Although mutations in the Huntingtin gene (HTT) due to polyQ expansion are known to cause neuropathology in humans (Huntington's disease, HD), the normal function(s) of the huntingtin gene and its product remains obscure. The principal aim of this thesis was to gain a better understanding of the evolution, function and genetics of the huntingtin gene using the invertebrate chordate Ciona intestinalis.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.505445  DOI: Not available
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