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Title: A framework for decision support, capture and re-use
Author: Adelmann, Holger Georg
Awarding Body: Loughborough University
Current Institution: Loughborough University
Date of Award: 2008
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Pharmaceutical Research and Development (R&D) is a 'knowledge intensive' business, requiring frequent and comprehensive knowledge transactions. One necessary class of knowledge transactions concerns the constant evaluation of incoming data from experiments, discussion of the data amongst scientists and physicians and the ability to make informed operational and strategic decisions amidst some uncertainty, particularly in the early phase of development. Because of these uncertainties, it is important to constantly review decisions to verify their validity as a drug development project moves on. As the decision-making is inextricably bound to appropriate risk awareness and risk management, the consideration of options and appropriate scenario planning, the application of past experience to present information will help provide a balanced assessment of risks prior to decision making. The author's research has used a combination of pilot studies, brainstorming sessions, review meetings and surveys combined with actual working 3 practice in an iterative manner, which has been proven useful to address the specific aims and objectives for the development, implementation and testing of a decision support framework for clinical drug development called EPISTEME.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available