Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502354
Title: Comparison of test cell designs for permeability evaluation of haemodialysis membranes
Author: Ebdiwi, Nouri
Awarding Body: The University of Strathclyde
Current Institution: University of Strathclyde
Date of Award: 2008
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Abstract:
The dialysis membrane is a key component of the haemodialyser. Determination of the membrane solute permeation and ultrafiltration characteristics is important in predicting haemodialyser performance. In some membrane permeation test cells, there are additional mass transfer resistances present due to fluid films adjacent to the membrane surface. This can mask the true permeability of the membrane. Test cell designs should therefore seek to minimise or eliminate any fluid film resistances In this project, solute permeability results were compared using two types of permeation test cells, namely a radial flow cell and a dynamic test cell. In the radial flow cell, fluid streams are directed perpendicular to the membrane surfaces in an attempt to reduce the fluid film thickness. In the dynamic test cell, the fluid streams are passed at high velocity through an open-pore rigid metal support structure that generates localised mixing at the membrane surfaces. Fluid film resistances are proportionately greater for the transfer of low molecular weight solutes and for high flux membranes. Therefore, the transfer of urea (60 mol wt) was studied in a polyacrylonitrile-based membrane AN69ST. Permeability of a higher molecular weight solute, caffeine, (194.2 mol wt) was also determined.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.502354  DOI: Not available
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