Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502338
Title: Hyperthermia with HIFU and multimodal examination of ex vivo poultry tissue
Author: Robertson, Craig
Awarding Body: The University of Strathclyde
Current Institution: University of Strathclyde
Date of Award: 2007
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Abstract:
High intensity focused ultrasound (HIFU) can be used to induce thermal ablation and cavitation for therapy. This paper considers thermal ablation. Despite intensive exploration of this topic, the relative contribution of HIFU's thermal effects for tumour destruction is not yet fully defined, because of a lack of standardised parameters. Additionally, observation of the extent of tissue damage on ex vivo specimens tends to be limited to histology. The present work began with the design and fabrication of a focused ultrasonic (925 kHz) transducer, and then sought to examine the feasibility of generating lesions in ex vivo poultry tissue, submerged in degassed water. Basic characterisation of the transducer and the 'ultrasonic field was carried out, with peak intensity determined to be approximately 300 W.cm⁻², followed by development of an appropriate experimental system to house both the transducer and the tissue.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.502338  DOI: Not available
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