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Title: Nitric oxide, salivary hypofunction and Sjogren's syndrome
Author: Caulfield, Vicky Louise
Awarding Body: University of Liverpool
Current Institution: University of Liverpool
Date of Award: 2008
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Sjogren's syndrome is a systemic autoimmune disorder which specifically targets the glands, primarily the salivary and lacrimal glands and leads to an impairment of secretory function and is characterised by lymphocytic infiltration of the salivary and lacrimal glands. Until relatively recently it was believed that the glandular function was a direct consequence of immune mediated destruction of the :inar tissue but most recent data suggests that the glandular hypofunction is more 5ly to be the result of immune mediated inhibition of acinar function, which if prolonged could lead to acinar atrophy.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available