Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501273
Title: Mimicking the enzyme active site of haloperoxidase and acid phosphates
Author: Tapper, Sophia Christina
Awarding Body: University of Exeter
Current Institution: University of Exeter
Date of Award: 2009
Availability of Full Text:
Access through EThOS:
Abstract:
This thesis describes the background and research applied to the area of metalloenzymes focusing on vanadium haloperoxidases and acid phosphatases. Using the information on the structure of the active sites of these enzymes, the disciplines of host-guest and supramolecular chemistry were applied to design a library of receptors (hosts) that were organically synthesised In the laboratory. A majority of these receptors were shown by MNR titrations to bind phosphate and/or vanadate, structurally and functionally mimicking the active sites of these enzymes.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.501273  DOI: Not available
Share: