Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500912
Title: Defining genes that regulate the differentiation status of neuroblastoma cell lines
Author: Sung, Pei-Ju
Awarding Body: University of Newcastle Upon Tyne
Current Institution: University of Newcastle upon Tyne
Date of Award: 2009
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Abstract:
Defects in differenfiafion are one of the major events presented in highly malignant leuroblastoma tumours. Evidence suggests differentiated neuroblastomas are Lssociated with improved patient outcome, but little is known regarding the molecular regulafion of differenfiation in vitro and in vivo. Although differentiation can be induced by alternative treatments, we hypothesise that there are some genes in common that become altered and a subset of these regulate the differentiation process in neuroblastoma cells. In conclusion, a set of candidate genes were identified to be involved in the regulation of neuroblastoma cell differentiation.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.500912  DOI: Not available
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