Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.496089
Title: Investigation on the role of lipids in the regulation of protein function
Author: Tsaloglou, Maria-Nefeli
Awarding Body: University of Southampton
Current Institution: University of Southampton
Date of Award: 2008
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Abstract:
Type 11 amphiphiles have been shown in vitro to activate the catalytic activity of ate-determining enzyme of lipid metabolism CTP: phosphocholine cytidylyltransferase (CCT). Membrane stored curvature elastic stress has been suggested as a regulator of CCT activity. It has been postulated that Type II lipids, which form membranes with high curvature elastic stress, activate CCT by increasing the partitioning of CCT onto the membrane. Conversely, Type I lipids inhibit CCT activity by decreaskig stored elastic energy.
Supervisor: Attard, George Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.496089  DOI: Not available
Keywords: QD Chemistry
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