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Title: Calcium regulation and ion channel remodelling in an animal model of heart failure
Author: Diffley, Leonie
ISNI:       0000 0001 3424 3172
Awarding Body: Manchester University
Current Institution: University of Manchester
Date of Award: 2008
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CHF is a complex disease that results in the remodelling of the heart at every level, from the gross anatomy down to the levels of the ion channel resulting in aberrant signalling and contractile dysfunction. The QT interval of the cardiac ECG is frequently increased in heart failure, suggesting ion channel remodelling which has proarrhythmic consequences. One of the aims of this study was to determine the changes that occur from the in vivo level, down to the level of the ion channel that may contribute to arrhythmogenesis.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available