Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493649
Title: The role of DNMT1 inhibition in the identification of epigenetically silenced genes in pituitary tumours
Author: Dudley, Kevin
Awarding Body: Keele University
Current Institution: Keele University
Date of Award: 2009
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Abstract:
Epigenetic unmasking, either by pharmacological inhibition or direct gene targeting, has been utilised to identify novel tumour suppressor genes that are silenced in association with inappropriate CpG island (CGI) methylation in various types of cancer. In this study, an epigenetic unmasking strategy was developed to identify novel genes that are silenced in association with inappropriate, CGI methylation in pituitary tumours.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.493649  DOI: Not available
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