Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493435
Title: The genetics of psoriatic arthritis
Author: Ho, Pauline Y. P. Dr
Awarding Body: University of Manchester
Current Institution: University of Manchester
Date of Award: 2007
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Abstract:
Psoriatic arthritis (PsA) has a strong genetic predilection with the first-degree relatives of PsA cases having an increased risk of developing the disease and the sibling recurrence risk (λs) estimated to be as high as 55. Due to the" overlap of PsA with psoriasis aTid other inflammatory arthritis (lA) such as rheumatoid arthritis (RA), in order to dissect out genetic factors contributing to the aetiology of PsA over and above those that contribute to psoriasis alone and lA alone, a unique study design was used whereby allele frequencies for the genetic polymorphisms tested were compared between patients with PsA and three control cohorts: psoriasis alone, lA alone and healthy controls.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.493435  DOI: Not available
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