Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493403
Title: The actions of a soft coral derived natural product on neurones
Author: Woolley, David
Awarding Body: University of Aberdeen
Current Institution: University of Aberdeen
Date of Award: 2008
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Abstract:
The effects of a soft coral derived product and its major active component, 3-carboxyl-methylpyridinium (CMP), were assessed in cultured neurones from dorsal root ganglion (DRG) and the hippocampus, and in hippocampal slices. Application of the soft coral preparation or CMP to cultured DRG neurones reduced an outward potassium current, causing attenuation of spike frequency adaptation. This evoked a switch to multiple firing in previously single firing DRG neurones.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.493403  DOI: Not available
Keywords: Neurons
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