Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493231
Title: Type II DNA topoisomerases in zebrafish development
Author: Azrak, Sami
Awarding Body: Newcastle University
Current Institution: University of Newcastle upon Tyne
Date of Award: 2008
Availability of Full Text:
Access through EThOS:
Abstract:
DNA topoisomerases are vital enzymes for major cellular processes like replication, transcription, and chromosome segregation. They play an essential role in solving DNA topological problems by catalysing the passage of DNA strands through each other via introducing transient single or double strand breaks. Type IIA DNA topoisomerases members introduce double strand breaks via an ATP-dependent strand passage reaction. This study aimed to investigate the roles of topo Ila and topo Iip in zebrafish development.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.493231  DOI: Not available
Share: