Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492856
Title: Characterisation of the expression and function of an E3 ubiquitin ligase, WWP1, in breast cancer
Author: Nguyen Huu, Ngoc-Sa
Awarding Body: Manchester University
Current Institution: University of Manchester
Date of Award: 2008
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Abstract:
WWP1 is a ubiquitin ligase of the Nedd4-protein like family. Previous analysis in our laboratory suggested a possible relationship between WWP1 expression and breast cancer. This work attempted to characterise WWP1 expression and potential function in breast oncology. WWP1 mRNA expression was found to be up regulated mostly in ER+ breast tumour cell lines compared with non tumourigenic cell lines. In our experiments, WWP1 expression was not activated by oestrogen.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.492856  DOI: Not available
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