Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490937
Title: Wetting and Spreading of Mucus
Author: Cowan, Nicola
Awarding Body: Heriot-Watt University
Current Institution: Heriot-Watt University
Date of Award: 2008
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Abstract:
The wetting and spreading of aqueous solutions of gastric pig mucin has been studied on both high-energy and low-energy surfaces. Static and dynamic contact angles of mucin droplets were measured directly on glass and collagen surfaces of both flat and fibre substrate geometries, using a novel laser-assisted measurement method. The surface tension of the mucin solutions were measured using the du Nouy ring ,.' method, and found to be independent of mucin concentration. // The non-Newtonian properties of mucus was further evidenced by the dynamic wetting on flat glass substrates; the change in contact angle and droplet radius with time could be described by a power law relation with exponents slightly smaller than that observed for Newtonian fluids which obey Tanner's law. The spreading kinetics of mucus on flat collagen substrates were shown to follow a different rule of spreading to that observed on flat glass substrates. Dynamic wetting studies on cylindrical fibre substrates were shown to differ significantly from that observed on flat substrates. Tanner's law was not obeyed for wetting on either glass or collagen fibres. The power law behaviour of the spreading ()(t) t -O.SS±O.06 mucin droplets was characterised by ~ on both glass and collagen fibres. All concentrations of mucus droplets exhibited measurable non-zero contact angles on fibre substrates, regardl~ss 'of the complete wetting nature on a chemically identical flat substrate.
Supervisor: Not available Sponsor: Not available
Qualification Name: Heriot-Watt University, 2008 Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.490937  DOI: Not available
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