Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490348
Title: Genetic and Epidemiological Studies in Multiple Sclerosis
Author: Ramagopalan, Sreeram
ISNI:       0000 0001 3506 0749
Awarding Body: Oxford
Current Institution: University of Oxford
Date of Award: 2008
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Abstract:
Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease which affects the central nervous system. With a prevalence of ~1/1,000 in Canada, MS is the most common cause of non-traumatic neurological disability in young adults. MS is unsurpassed for variability in disease outcome. Genetic epidemiological studies Indicate a significant genetic component for susceptibility but with the single exception of the HLA class II region, the search for susceptibility genes has met with limited success. Familial studies also show a maternal effect in disease risk as well as suggesting a role for genetics In determining disease progression.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.490348  DOI: Not available
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