Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.489418
Title: Molecular and genetic studies of Gemin3 using Drosophila melanosgastee
Author: Cauchi, Ruben J.
ISNI:       0000 0001 3525 2767
Awarding Body: Oxford University
Current Institution: University of Oxford
Date of Award: 2008
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Abstract:
The survival motor neuron (SMN) complex is a macromolecular structure composed of SMN, Gemin2-8 and Unrip. The best-documented function of the SMN complex concerns the assembly of the spliceosome building blocks, uridine-rich small nuclear ribonucleoproteins (UsnRNPs). SMN deficiency results in Spinal Muscular Atrophy, a disorder characterised by degeneration of spinal cord motor neurons and progressive muscular weakness.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.489418  DOI: Not available
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