Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.489365
Title: Investigations into the reactivity of thiols and disulfides at membrane interfaces
Author: Biojout, Alexandre Denis
ISNI:       0000 0001 3464 5905
Awarding Body: University of Sheffield
Current Institution: University of Sheffield
Date of Award: 2008
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Abstract:
The membrane is a key component of cells as it acts as a barrier with the extracellular matrix, preventing alien entities trom entering the cell unnindered. It also provides the medium for membrane embedded proteins to bind and react to small molecule messengers and with other cells. The research described in this thesis is focused on the study of the thiol-disulfide reaction at the membrane interfaces in order to understand how this environment affects reactivity and mechanism relative to aqueous solution. This knowledge informs the design of artificial biomimetic systems based on vesicles, which have long been used as the cell membrane model of choice.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.489365  DOI: Not available
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