Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.488988
Title: Cleavage-functionalisation reactions of a sulfur linker in the flurous synthesis of n-heterocycles
Author: James, Karen Morag
Awarding Body: Manchester
Current Institution: University of Manchester
Date of Award: 2007
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Abstract:
A fluorous, cyclative-capture strategy, based on a connective Pummerer-type process, has been developed for the rapid, one-pot construction of fluorous-tagged, heterocyclic frameworks. The process involves addition of a fluorous thiol, which triggers a Pummerer-type cyclisation resulting in the preparation of an N-heterocycle, the introduction of a fluorous tag and the construction of a sulfur linker. The fluorous tag then allows convenient purification of the tagged product from non-fluorous by-products through the use of Fluorous Solid Phase Extraction (FSPE)
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.488988  DOI: Not available
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