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Title: Leukocyte coping capacity and leukocyte activation as a measure of stress in wild badgers (Meles meles)
Author: Montes, I.
Awarding Body: Coventry University
Current Institution: Coventry University
Date of Award: 2008
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All living organisms are subject to some form of stress, which in medical terms is a response oftl1e body to a wide range of external s~~uli. This may be physiological or psychological in nature. Objective, quantitative and meaningful me~ures of stress are important to stud~es in many branches of vertebrate biology including humanbiology, animal husbandry and wildlife ecology. The effects of stress in animals have previously been assessed using a variety oftecJ:niques, such as me.asurement of cortisol, haematological values and behavioural observations. The aim ofthis study was to develop and validate novel techniques for quantifying stress·by directly measuring the immune response. Transport significantly reduced the number of cir~ulatingleukocytes (F2,24 = 5.4, . . P<0.05). The changes in neutrophil n~bers may have- occurred as a result of an alteration in adhesion receptors on the neutrophils (L-selectin; integrins and PSGL-l P-Selectin Glycoprotein Ligand-I) or the endothelium (p-selectin; Intracellular Adhesion·Molecule 1). Transport stress had a significant effect on baseline neutrophil activation (F2,19 = 12.4, P
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available