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Title: Study of long term visual function outcomes and ocular growth changes following congenital cataract surgery and intraocular lens implantation in children
Author: Hussin, Hussin Mohamed
ISNI:       0000 0001 3585 2818
Awarding Body: University of Bristol
Current Institution: University of Bristol
Date of Award: 2007
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Abstract:
The aim of this study was (1) to determine the relationship between early congenital cataract surgery with intraocular lens insertion and long term visual function outcome (2) to determine and quantify complications associated with this procedure. (3) and to evaluate the axial length and refractive changes in these children. Methods: Cases were identified by retrospective review of the hospital case-notes of all children who undergone congenital cataract surgery and intraocular lens implantation between 1987 and 1998 at Bristol Eye Hospital and who had completed a minimum follow up period of 5 years. Children were examined by the investigator who assessed their visual function. Results The median best-corrected visual acuity in individuals who had received unilateral cataract extraction was significantly poorer than that ofthe fellow eyes (P=O.OOl,Wilcoxon Signed Rank test). The visual acuity in the better eye of individuals who had received bilateral congenital cataracts extraction was significantly better than for the operated eye ofunilateral cataract extraction (P = O.OOl,Mann Whitney Test). There was no significant difference between the final axial length in the operated eyes in the unilateral cataract group and the right eyes in the control group (P=O.69,Mann Whitney test). There was no significant difference in axial length growth between the operated eyes of individuals who had received unilateral cataract extraction and the The aim of this study was (1) to determine the relationship between early congenital cataract surgery with intraocular lens insertion and long term visual function outcome (2) to determine and quantify complications associ\ed with this procedure. (3) and to evaluate the axial length and refractive changes in these children. Methods Cases were identified by retrospective review of the hospital case-notes of all children who undergone congenital cataract surgery and intraocular lens implantation between 1987 and 1998 at Bristol Eye Hospital and who had completed a minimum follow up period of 5 years. Children were examined by the investigator who assessed their visual function. Results The median best-corrected visual acuity in individuals who had received unilateral cataract extraction was significantly poorer than that ofthe fellow eyes (P=O.OOl,Wilcoxon Signed Rank test). The visual acuity in the better eye of individuals who had received bilateral congenital cataracts extraction was significantly better than for the operated eye ofunilateral cataract extraction (P = O.OOl,Mann Whitney Test). There was no significant difference between the final axial length in the operated eyes in the unilateral cataract group and the right eyes in the control group (P=O.69,Mann Whitney test). There was no significant difference in axial length growth between the operated eyes of individuals who had received unilateral cataract extraction and the The aim of this study was (1) to determine the relationship between early congenital cataract surgery with intraocular lens insertion and long term visual function outcome (2) to determine and quantify complications associ\ed with this procedure. (3) and to evaluate the axial length and refractive changes in these children. Methods Cases were identified by retrospective review of the hospital case-notes of all children who undergone congenital cataract surgery and intraocular lens implantation between 1987 and 1998 at Bristol Eye Hospital and who had completed a minimum follow up period of 5 years. Children were examined by the investigator who assessed their visual function. Results The median best-corrected visual acuity in individuals who had received unilateral cataract extraction was significantly poorer than that ofthe fellow eyes (P=O.OOl,Wilcoxon Signed Rank test). The visual acuity in the better eye of individuals who had received bilateral congenital cataracts extraction was significantly better than for the operated eye ofunilateral cataract extraction (P = O.OOl,Mann Whitney Test). There was no significant difference between the final axial length in the operated eyes in the unilateral cataract group and the right eyes in the control group (P=O.69,Mann Whitney test). There was no significant difference in axial length growth between the operated eyes of individuals who had received unilateral cataract extraction and the right eyes of those who had received bilateral cataract extraction. The myopic shift in the operated eyes of individuals who had received\nilateral cataract extraction was significantly greater than that in the fellow unoperated eyes. Conclusion In this sample, no major sight-threatening complications occurred. There was no significant retardation or elongation of axial length growth in the unilateral or bilateral cataract group. Although there was no significant difference in axial length between pseudophakic eyes and fellow eyes in the unilateral group there was a greater shift toward myopia in the pseudophakic eyes and this finding suggests that the myopic shift may be a result of stable intraocular lens power, with normal axial length elongation.
Supervisor: Not available Sponsor: Not available
Qualification Name: M.D.--University of Bristol, 2007 Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.486113  DOI: Not available
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